Nation sees therapeutics success
admin
2023-01-28 12:13:16
0

Pharmacists check prescription information at a fever clinic in Minhang district of Shanghai on Jan 8. The small molecule drugs to treat COVID-19 had been put into use in community health centers in Shanghai to better play their roles in "early detection, early intervention and early diversion". WANG XIANG/XINHUA

Domestically developed COVID-19 drug therapies lower risk of hospitalization

China will create broad-spectrum treatments to tackle mutated strains of the COVID-19 virus and develop drugs with novel mechanisms to fight the pathogen, according to a document provided to China Daily.

As of Jan 19, a total of 10 domestically made COVID-19 drugs had either been granted official or conditional market approval or were authorized to treat symptoms of the pathogen, the document stated.

The document was issued by the specialized team for COVID-19 medicine research and development under the Joint Prevention and Control Mechanism of the State Council, China's Cabinet.

China also had 23 drugs on the key COVID-19 medicine list that were in active development or undergoing real-world evidence studies after receiving market approval, it said.

"The team will continue to facilitate the development of safe and effective treatments that can cover the whole course of the disease and are suitable for all populations," it added.

Since the COVID-19 pandemic began, China's novel coronavirus drug development process has followed three broad technical paths- stopping the virus from entering cells, inhibiting viral replication in the body and regulating the body's immune system.

In December 2021, China granted official market approval to its first homegrown neutralizing monoclonal neutralizing antibody cocktails - BRII-196 and BRII-198. It is a combination therapy administered through intravenous infusion that can lower the risk of hospitalization and death by nearly 80 percent, according to its phase-three clinical trial results.

Meanwhile, Chinese scientists have been developing small-molecule oral treatments for COVID-19.A breakthrough came in July when China granted conditional authorization for the oral antiviral Azvudine to treat COVID-19. The drug was originally used to treat HIV.

This year, China will accelerate the development of small-molecule oral drugs. In mid-January, the National Medical Products Administration received applications for market approval for new antivirals SIM0417 and VV116. Another antiviral called RAY1216 had recently finished recruiting for its late-stage clinical trials.

Besides finding treatments for COVID-19, Chinese scientists are researching new drugs to prevent infections or regulate the body's immune system, with a handful of candidates currently in phase two or three clinical trials. Some notable examples include the targeted inhibitor drug TDI01 and HY3000 peptide nasal spray.

zhangzhihao@chinadaily.com.cn

相关内容

热门资讯

新还珠格格,欣荣和永琪有个孩子... 新还珠格格,欣荣和永琪有个孩子?不是说永琪从来都没碰过她吗?绵忆到底是他和小燕子的还是欣荣的啊求正解...
中级会计怎么备考?今年几月考试... 中级会计怎么备考?今年几月考试?您好,很高兴为您解答中级会计师考试,教材是根本和基础,所有的题目都是...
继兴业、招商、中信后,邮储银行... (来源:现代商业银行杂志)金融资产投资公司(AIC)队伍再添新员。邮储银行近日发布公告称,该行拟以自...
中央巡视组对陕西开展两个半月常... 转自:北京日报客户端日前,中央第十五巡视组进驻陕西省,将开展为期两个半月左右的常规巡视,并会同陕西省...
柳州幻境空间在哪里 柳州幻境空间在哪里柳州幻境空间是位于广西柳州市城中区华联商闷郑城4楼的室内主题乐园,提供了各种游戏和...
中央巡视组进驻山东 联动巡视济... 转自:央视新闻客户端经党中央批准,二十届中央第六轮巡视将对16个省(自治区、直辖市)开展常规巡视,并...
继续发布暴雨蓝色预警!北京等地... 转自:央视新闻客户端中央气象台19日早6时继续发布暴雨蓝色预警。预计,19日早8时至20日早8时,青...
降妖伏魔篇演员有哪些 降妖伏魔篇演员有哪些文章舒淇程小东黄勃
晚上十一点在河边抓鱼听到有人叫... 晚上十一点在河边抓鱼听到有人叫我小名声音跟我一个朋友一样,电筒照却没有发现有人而且我女朋友也听见了不...
属猴的为什么吸引属狗的人 属猴的为什么吸引属狗的人属相狗虽不善甜言蜜语,为人多有情感之被捉,然其铅轮内心却多有向往甜蜜幸福之生...